Substrate: Integrin beta 3 (Platelet membrane glycoprotein IIIa)
Seq-ID: O54890 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
integrin binding		 external side of plasma membrane integrin-mediated signaling pathway,
cell-matrix adhesion,
cell-substrate junction assembly
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 784 EATSTFTNITYRGT        - 14519852
LTP
1.00
 - Integrin_b_cyt
0.27
 --

Substrate: Integrin beta 3 (Platelet membrane glycoprotein IIIa)
Seq-ID: P05106 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-25081   ITAV_HUMAN
MINT-45900   EPS8_HUMAN
MINT-45905   RBGP1_HUMAN
MINT-45913   GULP1_HUMAN
MINT-45916   RGS12_HUMAN
MINT-45923   DAB1_MOUSE
MINT-45928   DAB2_MOUSE
MINT-45939   IRS1_RAT
MINT-45952   TLN1_MOUSE
MINT-45957   JIP1_HUMAN
MINT-45960   LIN10_CAEEL
MINT-61480   TENC1_HUMAN
MINT-61568   DOK1_MOUSE
MINT-61569   NUMB_MOUSE
MINT-1795026   TLN1_HUMAN
MINT-6794817   PTN1_HUMAN
MINT-7384376   SRC_MOUSE
MINT-7384444   LYN_HUMAN
MINT-7384460   YES_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor activity,
vascular endothelial growth factor receptor 2 binding,
identical protein binding,
platelet-derived growth factor receptor binding,
cell adhesion molecule binding		 integrin complex,
alphav-beta3 integrin-vitronectin complex,
platelet alpha granule membrane		 positive regulation of peptidyl-tyrosine phosphorylation,
positive regulation of endothelial cell proliferation,
regulation of bone resorption,
blood coagulation,
negative regulation of lipid transport,
tube development,
activation of protein kinase activity,
integrin-mediated signaling pathway,
positive regulation of vascular endothelial growth factor receptor signaling pathway,
negative regulation of lipid storage,
negative regulation of macrophage derived foam cell differentiation,
cell-matrix adhesion,
interspecies interaction between organisms,
smooth muscle cell migration,
negative regulation of lipoprotein metabolic process,
angiogenesis involved in wound healing,
positive regulation of endothelial cell migration,
negative regulation of low-density lipoprotein receptor biosynthetic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 773 AKWDTANNPLYKEATSTFTNI - 8631894
LTP
1.00
 GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB		 Integrin_b_cyt
0.26
 --
Y 773 AKWDTANNPLYKEATSTFTNI SRC 15699036
LTP
1.00
 GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB		 Integrin_b_cyt
0.26
 --
Y 773 AKWDTANNPLYKEATSTFTNI - 18088087
HTP
1.00
 GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB		 Integrin_b_cyt
0.26
 --
Y 773 AKWDTANNPLYKEATSTFTNI SRC 18398066
LTP
1.00
 GRB2 SH2;
PTPN11 SH2;
SHC1 PTB;
TLN1 PTB		 Integrin_b_cyt
0.26
 --
T 777 TANNPLYKEATSTFTNITYRG PDK-1 10896934
LTP
1.00
 - Integrin_b_cyt
0.27
 --
T 779 NNPLYKEATSTFTNITYRGT  PDK-1 10896934
LTP
1.00
 - Integrin_b_cyt
0.27
 --
Y 785 EATSTFTNITYRGT        SYK 8631894
LTP
0.98
 PTPN11 SH2;
SHC1 PTB;
SYK SH2		 Integrin_b_cyt
0.26
 --
Y 785 EATSTFTNITYRGT        SRC 8631894
LTP
0.98
 PTPN11 SH2;
SHC1 PTB;
SYK SH2		 Integrin_b_cyt
0.26
 --
Y 785 EATSTFTNITYRGT        - 18088087
HTP
0.98
 PTPN11 SH2;
SHC1 PTB;
SYK SH2		 Integrin_b_cyt
0.26
 --

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